BDBM50084224 (R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-morpholin-4-ylimino]-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL150342

SMILES CCCCOc1ccc(cc1)S(=O)(=O)N1C=C(C[C@@H]1C(=O)NO)NN1CCOCC1

InChI Key InChIKey=JYUUAPXGAQJXBY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084224   

TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084224((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-morpholin-...)
Affinity DataIC50: 293nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloprotease-1, MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084224((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-morpholin-...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084224((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-morpholin-...)
Affinity DataIC50: 196nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloprotease-7, MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed