BDBM50084218 (R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-piperazin-1-ylimino]-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL151331

SMILES CCCCOc1ccc(cc1)S(=O)(=O)N1C=C(C[C@@H]1C(=O)NO)NN1CCNCC1

InChI Key InChIKey=IIKWXGAHGMGLSQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084218   

TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084218((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-piperazin-...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084218((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-piperazin-...)
Affinity DataIC50: 343nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloprotease-7, MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084218((R)-1-(4-Butoxy-benzenesulfonyl)-4-[(Z)-piperazin-...)
Affinity DataIC50: 184nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloprotease-1, MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed