BDBM50084209 (R)-1-[4-(2-Methoxy-ethoxy)-benzenesulfonyl]-4-[(Z)-methoxyimino]-pyrrolidine-2-carboxylic acid hydroxyamide::CHEMBL357050

SMILES COCCOc1ccc(cc1)S(=O)(=O)N1C\C(C[C@@H]1C(=O)NO)=N/OC

InChI Key InChIKey=OECFBMNWNGPPFC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084209   

TargetMatrilysin(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084209((R)-1-[4-(2-Methoxy-ethoxy)-benzenesulfonyl]-4-[(Z...)
Affinity DataIC50: 612nMAssay Description:In vitro inhibition of matrilysin (Matrix metalloprotease-7, MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084209((R)-1-[4-(2-Methoxy-ethoxy)-benzenesulfonyl]-4-[(Z...)
Affinity DataIC50: 109nMAssay Description:In vitro inhibition of human recombinant collagenase-1 (Matrix metalloprotease-1, MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084209((R)-1-[4-(2-Methoxy-ethoxy)-benzenesulfonyl]-4-[(Z...)
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibitory activity against gelatinase-A (matrix metalloprotease-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50084209((R)-1-[4-(2-Methoxy-ethoxy)-benzenesulfonyl]-4-[(Z...)
Affinity DataIC50: 15nMAssay Description:In vitro inhibition activity of human recombinant stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed