BDBM50083950 (S)-(+)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid[(S)-(+)-m-nicotinylbenzoylalanine]::(S)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid::CHEMBL22740

SMILES N[C@@H](CC(=O)c1cccc(c1)[N+]([O-])=O)C(O)=O

InChI Key InChIKey=KBJZPNMDKSNLIZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50083950   

TargetKynurenine 3-monooxygenase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50083950((S)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid ...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50083950((S)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid ...)
Affinity DataIC50: 500nMAssay Description:Tested for inhibitory activity against kynurenine 3-hydroxylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetKynureninase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50083950((S)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid ...)
Affinity DataIC50: 6.00E+4nMAssay Description:Tested for inhibitory activity against kynureninase from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetKynurenine 3-monooxygenase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50083950((S)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid ...)
Affinity DataIC50: 900nMAssay Description:Inhibition of KMO in rat brain homogenates using kynurenine as substrate measured after 5 to 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed
TargetKynurenine 3-monooxygenase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50083950((S)-2-Amino-4-(3-nitro-phenyl)-4-oxo-butyric acid ...)
Affinity DataIC50: 900nMAssay Description:Inhibition of KMO in rat brain homogenates using kynurenine as substrate measured after 5 to 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2019
Entry Details Article
PubMed