BDBM50083934 4-(4-Chloro-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL23545::CHEMBL424806

SMILES OC(=O)C(=O)CC(=O)c1ccc(Cl)cc1

InChI Key InChIKey=REKRWOUHJMMFBQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083934   

TargetKynurenine 3-monooxygenase(Rat)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50083934(CHEMBL23545 | CHEMBL424806 | 4-(4-Chloro-phenyl)-2...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA excision repair protein ERCC-5(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50083934(CHEMBL23545 | CHEMBL424806 | 4-(4-Chloro-phenyl)-2...)
Affinity DataIC50: 1.27E+4nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50083934(CHEMBL23545 | CHEMBL424806 | 4-(4-Chloro-phenyl)-2...)
Affinity DataIC50: 1.93E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed