BDBM50083821 3-({1-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-propyl]-1H-indazole-5-carbonyl}-amino)-2-(2,4,6-trimethyl-benzenesulfonylamino)-propionic acid::CHEMBL346345

SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@@H](CNC(=O)c1ccc2n(CCCNC3=NCCN3)ncc2c1)C(O)=O

InChI Key InChIKey=JSQQOUSTKYAWEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083821   

TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083821(3-({1-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-propy...)
Affinity DataIC50: 57nMAssay Description:Inhibition of aggregation of human gel-purified platelets (GPIIbIIIa GPP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083821(3-({1-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-propy...)
Affinity DataIC50: 70nMAssay Description:Inhibition of adhesion of integrin beta-3-transfected HEK293 cells to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed