BDBM50083787 2-Amino-3-({5-[4-(1H-imidazol-2-ylamino)-butyl]-4,5-dihydro-isoxazole-3-carbonyl}-amino)-propionic acid::CHEMBL127503

SMILES N[C@@H](CNC(=O)C1=NOC(CCCCNc2ncc[nH]2)C1)C(O)=O

InChI Key InChIKey=FLRCFRLFEXWKEC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083787   

TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083787(2-Amino-3-({5-[4-(1H-imidazol-2-ylamino)-butyl]-4,...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of platelet aggregation in human gel-purified platelets containing fibrinogen (GPP+Fg).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083787(2-Amino-3-({5-[4-(1H-imidazol-2-ylamino)-butyl]-4,...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50083787(2-Amino-3-({5-[4-(1H-imidazol-2-ylamino)-butyl]-4,...)
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of platelet aggregation in human platelet rich plasma (PRP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed