BDBM50083672 18-methyl-10-oxa-6,7,18-triazahexacyclo[9.9.1.01,9.02,17.04,8.015,21]henicosa-4(8),5,11,13,15(21)-pentaene-2,12-diol::CHEMBL112035

SMILES CN1CCC23C4Oc5c2c(CC1C3(O)Cc1cn[nH]c41)ccc5O

InChI Key

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50083672   

TargetDelta-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50083672(18-methyl-10-oxa-6,7,18-triazahexacyclo[9.9.1.01,9...)
Affinity DataEC50:  25nMAssay Description:Agonistic activity against human opioid Delta receptor transfected into Chinese hamster ovary (CHO) cells using [3H]Cl-DPDPE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50083672(18-methyl-10-oxa-6,7,18-triazahexacyclo[9.9.1.01,9...)
Affinity DataEC50:  19nMAssay Description:Agonistic activity against human opioid Mu receptor transfected into Chinese hamster ovary (CHO) cells using [3H]-DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50083672(18-methyl-10-oxa-6,7,18-triazahexacyclo[9.9.1.01,9...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity towards human opioid Mu receptor transfected into Chinese hamster ovary (CHO) cells using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50083672(18-methyl-10-oxa-6,7,18-triazahexacyclo[9.9.1.01,9...)
Affinity DataKi:  12nMAssay Description:Agonistic activity against human opioid Kappa receptor transfected into Chinese hamster ovary (CHO) cells using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50083672(18-methyl-10-oxa-6,7,18-triazahexacyclo[9.9.1.01,9...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards human opioid Delta receptor transfected into Chinese hamster ovary (CHO) cells using [3H]Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed