BDBM50083670 19-methyl-7-phenyl-11-oxa-6,8,19-triazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol::CHEMBL112656

SMILES CN1CCC23C4Oc5c2c(CC1C3(O)Cc1cnc(nc41)-c1ccccc1)ccc5O

InChI Key

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50083670   

TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50083670(19-methyl-7-phenyl-11-oxa-6,8,19-triazahexacyclo[1...)
Affinity DataEC50:  58nMAssay Description:Agonistic activity against human opioid Mu receptor transfected into Chinese hamster ovary (CHO) cells using [3H]-DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50083670(19-methyl-7-phenyl-11-oxa-6,8,19-triazahexacyclo[1...)
Affinity DataEC50:  24nMAssay Description:Agonistic activity against human opioid Delta receptor transfected into Chinese hamster ovary (CHO) cells using [3H]Cl-DPDPE as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50083670(19-methyl-7-phenyl-11-oxa-6,8,19-triazahexacyclo[1...)
Affinity DataEC50:  1.42E+3nMAssay Description:Agonistic activity against human opioid Kappa receptor transfected into Chinese hamster ovary (CHO) cells using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50083670(19-methyl-7-phenyl-11-oxa-6,8,19-triazahexacyclo[1...)
Affinity DataKi:  6.5nMAssay Description:Binding affinity towards human opioid Delta receptor transfected into Chinese hamster ovary (CHO) cells using [3H]Cl-DPDPE as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50083670(19-methyl-7-phenyl-11-oxa-6,8,19-triazahexacyclo[1...)
Affinity DataKi:  7.30nMAssay Description:Binding affinity towards human opioid Mu receptor transfected into Chinese hamster ovary (CHO) cells using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50083670(19-methyl-7-phenyl-11-oxa-6,8,19-triazahexacyclo[1...)
Affinity DataKi:  45nMAssay Description:Agonistic activity against human opioid Kappa receptor transfected into Chinese hamster ovary (CHO) cells using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed