BDBM50083595 3-[3-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]-benzoic acid::CHEMBL25734

SMILES N[C@@H](CS)CNc1cccc(Oc2cccc(c2)C(O)=O)c1

InChI Key InChIKey=PTYARAMVADWAJN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083595   

LigandPNGBDBM50083595(3-[3-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of bovine Farnesyltransferase in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50083595(3-[3-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of Geranylgeranyl transferase type I, an enzyme that recognizes CaaX sequences containing leucine as the terminal residue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50083595(3-[3-((R)-2-Amino-3-mercapto-propylamino)-phenoxy]...)
Affinity DataIC50: 250nMAssay Description:Inhibition of the Farnesyltransferase catalyzed incorporation of [3H]FPP into recombinant Ha-Ras by 50% in bovine brain at a concentration of ca. 1 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article