BDBM50083530 4-(4-Iodo-phenyl)-1-methyl-piperidine-4-carboxylic acid ethyl ester::CHEMBL113479::CHEMBL536264

SMILES CCOC(=O)C1(CCN(C)CC1)c1ccc(I)cc1

InChI Key InChIKey=BNYWEVINFWDOAV-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50083530   

TargetSodium-dependent serotonin transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(CHEMBL536264 | CHEMBL113479 | 4-(4-Iodo-phenyl)-1-...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter (SERT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(CHEMBL536264 | CHEMBL113479 | 4-(4-Iodo-phenyl)-1-...)
Affinity DataKi:  21.1nMAssay Description:Displacement of [3H]citalopram from serotonin transporter in Sprague-Dawley rat brain after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(CHEMBL536264 | CHEMBL113479 | 4-(4-Iodo-phenyl)-1-...)
Affinity DataKi:  21.1nMAssay Description:Inhibition of [3H]paroxetine binding to rat serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(CHEMBL536264 | CHEMBL113479 | 4-(4-Iodo-phenyl)-1-...)
Affinity DataKi:  2.35E+3nMAssay Description:Inhibition of [3H]DAMGO binding to mu-opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(CHEMBL536264 | CHEMBL113479 | 4-(4-Iodo-phenyl)-1-...)
Affinity DataKi:  3.25E+3nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporter (DAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(CHEMBL536264 | CHEMBL113479 | 4-(4-Iodo-phenyl)-1-...)
Affinity DataKi:  3.25E+3nMAssay Description:Displacement of [3H]WIN 35428 from dopamine transporter in Sprague-Dawley rat brain after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(CHEMBL536264 | CHEMBL113479 | 4-(4-Iodo-phenyl)-1-...)
Affinity DataKi:  3.25E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to rat dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(CHEMBL536264 | CHEMBL113479 | 4-(4-Iodo-phenyl)-1-...)
Affinity DataKi:  5.19E+5nMAssay Description:Displacement of [3H]nisoxetine from norepinephrine transporter in Sprague-Dawley rat frontal cortex after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetTransporter(Rat)
University of New Orleans

Curated by ChEMBL
LigandPNGBDBM50083530(CHEMBL536264 | CHEMBL113479 | 4-(4-Iodo-phenyl)-1-...)
Affinity DataKi:  5.19E+5nMAssay Description:Inhibition of [3H]-nisoxetine binding to rat norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed