BDBM50083444 CHEMBL357974::[1-(2-Aminomethyl-3H-imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone

SMILES NCc1ncc(CN2CCN(Cc3ccccc23)C(=O)c2cccc3ccccc23)[nH]1

InChI Key InChIKey=YQLBBXJKCBUELQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083444   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083444([1-(2-Aminomethyl-3H-imidazol-4-ylmethyl)-1,2,3,5-...)
Affinity DataIC50: 840nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed