BDBM50083426 3-(3H-Imidazol-4-yl)-1-[(S)-2-(2-methoxy-ethyl)-4-(naphthalene-1-carbonyl)-piperazin-1-yl]-propan-1-one::CHEMBL151882

SMILES COCC[C@H]1CN(CCN1C(=O)CCc1cnc[nH]1)C(=O)c1cccc2ccccc12

InChI Key InChIKey=KOPFKVBGCBJMOI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083426   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083426(3-(3H-Imidazol-4-yl)-1-[(S)-2-(2-methoxy-ethyl)-4-...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed