BDBM50083425 CHEMBL342079::[1-(1H-Imidazol-2-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone

SMILES O=C(N1CCN(Cc2ncc[nH]2)c2ccccc2C1)c1cccc2ccccc12

InChI Key InChIKey=ILEJZWJHUAYCEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083425   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083425([1-(1H-Imidazol-2-ylmethyl)-1,2,3,5-tetrahydro-ben...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed