BDBM50083416 CHEMBL151633::N-[1-(3H-Imidazol-4-ylmethyl)-4-(naphthalene-1-carbonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-8-yl]-benzenesulfonamide

SMILES O=C(N1CCN(Cc2cnc[nH]2)c2cc(NS(=O)(=O)c3ccccc3)ccc2C1)c1cccc2ccccc12

InChI Key InChIKey=LUWZAQHNTQFUNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083416   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50083416(N-[1-(3H-Imidazol-4-ylmethyl)-4-(naphthalene-1-car...)
Affinity DataIC50: 2.49E+5nMAssay Description:Inhibitory activity against human purified recombinant farnesyltransferase (hFT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed