BDBM50083224 3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-1-phenyl-propan-1-ol::CHEMBL28821

SMILES OC(CCN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)c1ccccc1

InChI Key InChIKey=PSBXDOYFPJDNNH-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50083224   

TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083224(3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-1-phe...)
Affinity DataIC50: 1.48E+3nMAssay Description:Reuptake inhibition of [3H]-5-HT (5-HT) in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083224(3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-1-phe...)
Affinity DataIC50: 7.03nMAssay Description:Reuptake inhibition of [3H]-labeled dopamine (DA) in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083224(3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-1-phe...)
Affinity DataKi:  6.09nMAssay Description:Binding affinity against dopamine transporter labelled with [125I]- RTI-55 in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083224(3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-1-phe...)
Affinity DataKi:  6.10nMAssay Description:Binding affinity towards dopamine transporter (DAT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083224(3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-1-phe...)
Affinity DataKi:  700nMAssay Description:Binding affinity against Serotonin transporter (SERT) labelled with [125I]RTI-55 in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083224(3-[4-(2-Benzhydryloxy-ethyl)-piperazin-1-yl]-1-phe...)
Affinity DataKi:  700nMAssay Description:Binding affinity towards rat serotonin transporter (SERT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed