BDBM50083208 1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[3-(3-methoxy-phenyl)-propyl]-piperazine::CHEMBL149013

SMILES COc1cccc(CCCN2CCN(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c1

InChI Key InChIKey=YJZOCKRJFJPMEO-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50083208   

TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083208(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[3-(...)
Affinity DataIC50: 6.5nMAssay Description:Reuptake inhibition of [3H]-labeled dopamine (DA) in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083208(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[3-(...)
Affinity DataIC50: 265nMAssay Description:Reuptake inhibition of [3H]-5-HT (5-HT) in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083208(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[3-(...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity against dopamine transporter labelled with [125I]- RTI-55 in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50083208(1-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-4-[3-(...)
Affinity DataKi:  100nMAssay Description:Binding affinity against Serotonin transporter (SERT) labelled with [125I]RTI-55 in rat.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed