BDBM50083049 5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-isoxazole-3-carboxylic acid::CHEMBL144058

SMILES CC1(C)CCC(C)(C)c2cc(ccc12)-c1cc(no1)C(O)=O

InChI Key InChIKey=NHCDZDYMLCAHIV-UHFFFAOYSA-N

Data  5 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50083049   

TargetRetinoic acid receptor gamma(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083049(5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataEC50: >1.00E+3nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor gamma(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083049(5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKd:  8.80E+3nMAssay Description:In vitro binding affinity for Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083049(5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataEC50: >1.00E+3nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083049(5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKd:  5.10E+3nMAssay Description:In vitro binding affinity for Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083049(5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKd:  2.80E+4nMAssay Description:In vitro binding affinity for Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083049(5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKd: >1.00E+5nMAssay Description:In vitro binding affinity for Retinoid X receptor RXR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50083049(5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Affinity DataKd:  2.10E+4nMAssay Description:In vitro binding affinity for Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed