BDBM50082920 6-Carbazol-9-ylmethyl-pteridine-2,4-diamine::CHEMBL423200

SMILES Nc1nc(N)c2nc(Cn3c4ccccc4c4ccccc34)cnc2n1

InChI Key InChIKey=IEDDLXNDDDZXMU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082920   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082920(6-Carbazol-9-ylmethyl-pteridine-2,4-diamine | CHEM...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082920(6-Carbazol-9-ylmethyl-pteridine-2,4-diamine | CHEM...)
Affinity DataIC50: 55nMAssay Description:Inhibitory activity against DHFR (Dihydrofolate reductase) from Rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50082920(6-Carbazol-9-ylmethyl-pteridine-2,4-diamine | CHEM...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against DHFR (Dihydrofolate reductase) from Pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed