BDBM50082666 4-(Dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]benzenecarboxamide::4-Dimethylamino-N-(5-hydroxycarbamoyl-pentyl)-benzamide::CHEMBL46942

SMILES CN(C)c1ccc(cc1)C(=O)NCCCCCC(=O)NO

InChI Key InChIKey=RGWSSTALGUXZMU-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50082666   

TargetHistone deacetylase 2b(Maize)
WestfäLische Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50082666(4-Dimethylamino-N-(5-hydroxycarbamoyl-pentyl)-benz...)
Affinity DataIC50: 100nMAssay Description:Inhibition of maize Histone deacetylase 2 (HD-2) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 2b(Maize)
WestfäLische Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50082666(4-Dimethylamino-N-(5-hydroxycarbamoyl-pentyl)-benz...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against maize Histone deacetylase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetHistone deacetylase(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50082666(4-Dimethylamino-N-(5-hydroxycarbamoyl-pentyl)-benz...)
Affinity DataIC50: 152nMAssay Description:Inhibitory activity against histone deacetylase (HDAC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2018
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50082666(4-Dimethylamino-N-(5-hydroxycarbamoyl-pentyl)-benz...)
Affinity DataIC50: 244nMAssay Description:Concentration required to inhibit human Histone deacetylase (HDAC) enzyme by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50082666(4-Dimethylamino-N-(5-hydroxycarbamoyl-pentyl)-benz...)
Affinity DataIC50: 153nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50082666(4-Dimethylamino-N-(5-hydroxycarbamoyl-pentyl)-benz...)
Affinity DataIC50: 216nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50082666(4-Dimethylamino-N-(5-hydroxycarbamoyl-pentyl)-benz...)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibitory concentration against human histone deacetylase (HDAC) from HeLa cells with substrate 5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50082666(4-Dimethylamino-N-(5-hydroxycarbamoyl-pentyl)-benz...)
Affinity DataIC50: 640nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 5aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed