BDBM50082657 4-Dimethylamino-N-(7-hydroxycarbamoyl-heptyl)-benzamide::CHEMBL143047

SMILES CN(C)c1ccc(cc1)C(=O)NCCCCCCCC(=O)NO

InChI Key InChIKey=NMUMGBKBHOJAQD-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50082657   

TargetHistone deacetylase 2b(Maize)
WestfäLische Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50082657(4-Dimethylamino-N-(7-hydroxycarbamoyl-heptyl)-benz...)
Affinity DataIC50: 300nMAssay Description:Inhibition of maize Histone deacetylase 2 (HD-2) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 2b(Maize)
WestfäLische Wilhelms-UniversitäT MüNster

Curated by ChEMBL
LigandPNGBDBM50082657(4-Dimethylamino-N-(7-hydroxycarbamoyl-heptyl)-benz...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against maize Histone deacetylase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50082657(4-Dimethylamino-N-(7-hydroxycarbamoyl-heptyl)-benz...)
Affinity DataIC50: 2.18E+3nMAssay Description:Concentration required to inhibit the partially purified HDAC enzyme by 50% obtained from H1299 cell lysateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50082657(4-Dimethylamino-N-(7-hydroxycarbamoyl-heptyl)-benz...)
Affinity DataIC50: 145nMAssay Description:Concentration required to inhibit human Histone deacetylase (HDAC) enzyme by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Rat)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50082657(4-Dimethylamino-N-(7-hydroxycarbamoyl-heptyl)-benz...)
Affinity DataIC50: 256nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Rat)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50082657(4-Dimethylamino-N-(7-hydroxycarbamoyl-heptyl)-benz...)
Affinity DataIC50: 488nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Rat)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50082657(4-Dimethylamino-N-(7-hydroxycarbamoyl-heptyl)-benz...)
Affinity DataIC50: 241nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 5bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed