BDBM50082513 CHEMBL141560::[2-(4'-Fluoro-biphenyl-4-sulfonyl)-3-hydroxycarbamoyl-1,2,3,4-tetrahydro-isoquinolin-7-yl]-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)Nc1ccc2CC(N(Cc2c1)S(=O)(=O)c1ccc(cc1)-c1ccc(F)cc1)C(=O)NO

InChI Key InChIKey=IGRVUOPMHNISAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082513   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082513([2-(4'-Fluoro-biphenyl-4-sulfonyl)-3-hydroxycarbam...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082513([2-(4'-Fluoro-biphenyl-4-sulfonyl)-3-hydroxycarbam...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed