BDBM50082438 CHEMBL141674::Oxo-[2-(4-phenoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-acetic acid

SMILES OC(=O)C(=O)C1Cc2ccccc2CN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=PZNZBFBEAZCEQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082438   

TargetStromelysin-1(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082438(Oxo-[2-(4-phenoxy-benzenesulfonyl)-1,2,3,4-tetrahy...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50082438(Oxo-[2-(4-phenoxy-benzenesulfonyl)-1,2,3,4-tetrahy...)
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed