BDBM50082414 1'-(4-phenylbutyl)spiro[1,3-dihydrobenzo[e]isobenzofuran-3,4'-(hexahydropyridine)]::CHEMBL113326

SMILES C(CCc1ccccc1)CN1CCC2(CC1)OCc1c2ccc2ccccc12

InChI Key InChIKey=UNBQZPWOJXNGJG-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082414   

Target5-hydroxytryptamine receptor 1A(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50082414(1'-(4-phenylbutyl)spiro[1,3-dihydrobenzo[e]isobenz...)
Affinity DataEC50: >1.00E+4nMAssay Description:Stimulation of [35S]- GIPyS binding to cloned human 5-hydroxytryptamine 1A receptor stably expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50082414(1'-(4-phenylbutyl)spiro[1,3-dihydrobenzo[e]isobenz...)
Affinity DataKi:  28nMAssay Description:Displacement of specific [3H]- citalopram binding to 5-HT uptake site in rat whole cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50082414(1'-(4-phenylbutyl)spiro[1,3-dihydrobenzo[e]isobenz...)
Affinity DataKi:  72nMAssay Description:Displacement of specific [3H]- 5-HT binding to cloned human 5-hydroxytryptamine 1A receptor stably expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed