BDBM50082411 1-(5-fluoro-3,4-dihydro-2H-8-chromenyloxy)-3-spiro[1,3-dihydrobenzo[e]isobenzofuran-3,4'-(hexahydropyridine)]-1-yl-2-propanol::CHEMBL111021

SMILES OC(COc1ccc(F)c2CCCOc12)CN1CCC2(CC1)OCc1c2ccc2ccccc12

InChI Key InChIKey=NSNNZSICHPTFIP-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082411   

Target5-hydroxytryptamine receptor 1A(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50082411(1-(5-fluoro-3,4-dihydro-2H-8-chromenyloxy)-3-spiro...)
Affinity DataEC50: >1.00E+4nMAssay Description:Stimulation of [35S]- GIPyS binding to cloned human 5-hydroxytryptamine 1A receptor stably expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50082411(1-(5-fluoro-3,4-dihydro-2H-8-chromenyloxy)-3-spiro...)
Affinity DataKi:  2.80nMAssay Description:Displacement of specific [3H]- 5-HT binding to cloned human 5-hydroxytryptamine 1A receptor stably expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50082411(1-(5-fluoro-3,4-dihydro-2H-8-chromenyloxy)-3-spiro...)
Affinity DataKi:  49nMAssay Description:Displacement of specific [3H]- citalopram binding to 5-HT uptake site in rat whole cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed