BDBM50082325 CHEMBL99392

SMILES [H][C@]12CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCCC(=O)NO)NC2=O

InChI Key InChIKey=FQWUNUXAOHTLLG-UHFFFAOYSA-N

Data  5 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50082325   

TargetHistone deacetylase(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50082325(CHEMBL99392)
Affinity DataIC50: 2nMAssay Description:Concentration required to inhibit Histone Deacetylase (HDAC) from K562 erythroleukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details Article
PubMed
TargetHistone deacetylase(Rat)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50082325(CHEMBL99392)
Affinity DataIC50: 349nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Rat)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50082325(CHEMBL99392)
Affinity DataIC50: 66nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 5bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Rat)
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50082325(CHEMBL99392)
Affinity DataIC50: 411nMAssay Description:Inhibitory activity against rat liver Histone deacetylase with substrate 3bMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50082325(CHEMBL99392)
Affinity DataKi:  0.130nMAssay Description:Binding affinity to HDAC2 (unknown origin) assessed as inhibition constant(ki,1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50082325(CHEMBL99392)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to HDAC3 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50082325(CHEMBL99392)
Affinity DataKi:  0.600nMAssay Description:Binding affinity to HDAC1 (unknown origin) assessed as inhibition constant(ki,1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50082325(CHEMBL99392)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to HDAC3 (unknown origin) assessed as inhibition constant(ki,1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50082325(CHEMBL99392)
Affinity DataKi:  34nMAssay Description:Binding affinity to recombinant human HDAC6 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate measured after 60 mins assessed as inhibition constant (ki,1) b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed