BDBM50081959 (S)-3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-carbonitrile::CHEMBL135908

SMILES FC[C@@H]1Cc2ccc(cc2CN1)C#N

InChI Key InChIKey=UYOIEPOOLGXPIW-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081959   

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50081959((S)-3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline...)
Affinity DataKi:  3.50E+3nMAssay Description:In vitro inhibition of PNMT (Phenylethanolamine N-Methyltransferase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50081959((S)-3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibitory constant against bovine phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50081959((S)-3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibitory constant against human phenylethanolamine N-methyl-transferase over-expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed