BDBM50081864 (2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-methylmethan-2-ylsulfonamido)methyl)-4-oxo-4-(piperidin-1-yl)butanamide::(2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-methylmethylsulfonamido)methyl)-4-oxo-4-(piperidin-1-yl)butanamide::(2R,3R)-3-Cyclopentylmethyl-N-hydroxy-2-[(methanesulfonyl-methyl-amino)-methyl]-4-oxo-4-piperidin-1-yl-butyramide::CHEMBL98044

SMILES CN(C[C@@H]([C@@H](CC1CCCC1)C(=O)N1CCCCC1)C(=O)NO)S(C)(=O)=O

InChI Key InChIKey=MVRHXCGLUWVMKH-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50081864   

TargetInterstitial collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 6nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 900nMAssay Description:Inhibition of Gel-A MMP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Strom-1 MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 200nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 400nMAssay Description:Inhibition of Coll-3 MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 400nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 900nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 6nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 891nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 398nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081864((2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-2-((N-meth...)
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed