BDBM50081576 2-(5-Chloro-thiophen-2-yl)-7-methyl-1H-[1,8]naphthyridin-4-one::CHEMBL50613

SMILES Cc1ccc2c(O)cc(nc2n1)-c1ccc(Cl)s1

InChI Key InChIKey=MNNFLOIBRFNAKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081576   

TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50081576(2-(5-Chloro-thiophen-2-yl)-7-methyl-1H-[1,8]naphth...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50081576(2-(5-Chloro-thiophen-2-yl)-7-methyl-1H-[1,8]naphth...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of tubulin polymerization (ITP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed