BDBM50081569 2-(2,5-Dimethyl-thiophen-3-yl)-7-methyl-1H-[1,8]naphthyridin-4-one::CHEMBL412886

SMILES Cc1cc(c(C)s1)-c1cc(O)c2ccc(C)nc2n1

InChI Key InChIKey=MPOCYEDDQCUTMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081569   

TargetTubulin alpha-1A chain(Pig)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50081569(2-(2,5-Dimethyl-thiophen-3-yl)-7-methyl-1H-[1,8]na...)
Affinity DataIC50: 4.79E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50081569(2-(2,5-Dimethyl-thiophen-3-yl)-7-methyl-1H-[1,8]na...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of tubulin polymerization (ITP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed