BDBM50081552 CHEMBL3422063

SMILES CC[C@@H](NC(=O)c1ccc2[nH]nc(-c3ccc(OC4CCN(C)CC4)cc3)c2c1)c1ccccc1Cl

InChI Key InChIKey=XEADJJXUBNVGAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081552   

TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50081552(CHEMBL3422063)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of amino terminal GST-fused full length human TTK using His6-SUMO-TTK-N as substrate preincubated for 15 mins prior to ATP addition by ind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50081552(CHEMBL3422063)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of MPS1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed