BDBM50081469 CHEMBL3422045

SMILES NCCOc1ccc(cc1)C(=C1/CCc2ccccc12)\c1ccc(O)cc1

InChI Key InChIKey=BPDCIVIJDYKPRW-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081469   

TargetAromatase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50081469(CHEMBL3422045)
Affinity DataIC50: 493nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-trifluoromethylcoumarin as substrate assessed as formation of fluorescent metabolite after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50081469(CHEMBL3422045)
Affinity DataEC50:  3.18E+3nMAssay Description:Displacement of fluorescein-labeled ES2 from human recombinant ERalpha receptor after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50081469(CHEMBL3422045)
Affinity DataEC50:  1.35E+3nMAssay Description:Displacement of fluorescein-labeled ES2 from human recombinant ERbeta receptor after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed