BDBM50081408 CHEMBL3422042

SMILES NCCOc1ccc(cc1)C(=C(/Cn1cncn1)c1ccccc1)\c1ccc(O)cc1

InChI Key InChIKey=BRWXOOIUQMUMHI-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081408   

TargetAromatase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50081408(CHEMBL3422042)
Affinity DataIC50: 174nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-trifluoromethylcoumarin as substrate assessed as formation of fluorescent metabolite after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50081408(CHEMBL3422042)
Affinity DataEC50:  290nMAssay Description:Displacement of fluorescein-labeled ES2 from human recombinant ERalpha receptor after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50081408(CHEMBL3422042)
Affinity DataEC50:  519nMAssay Description:Displacement of fluorescein-labeled ES2 from human recombinant ERbeta receptor after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2016
Entry Details Article
PubMed