BDBM50081366 CHEMBL540331::[1-(4-Methoxy-3-phenethyloxy-benzyl)-4-methyl-pentyl]-propyl-amine; hydrochloride

SMILES CCCNC(CCC(C)C)Cc1ccc(OC)c(OCCc2ccccc2)c1

InChI Key InChIKey=FIQMWOKYPMJGTC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50081366   

TargetSigma non-opioid intracellular receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50081366([1-(4-Methoxy-3-phenethyloxy-benzyl)-4-methyl-pent...)
Affinity DataIC50: 190nMAssay Description:In vitro binding affinity at Sigma opioid receptor type 2 on guinea pig brain membranes by [3H]DTG displacement in the presence of [3H]pentazocine.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50081366([1-(4-Methoxy-3-phenethyloxy-benzyl)-4-methyl-pent...)
Affinity DataIC50: 210nMAssay Description:TIn vitro binding affinity at Sigma opioid receptor type 2 on guinea pig brain membranes by [3H]DTG displacement in the presence of [3H]pentazocine.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50081366([1-(4-Methoxy-3-phenethyloxy-benzyl)-4-methyl-pent...)
Affinity DataIC50: 1.80nMAssay Description:In vitro binding affinity at Sigma opioid receptors on guinea pig brain membranes by [3H]3-PPP displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50081366([1-(4-Methoxy-3-phenethyloxy-benzyl)-4-methyl-pent...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity at Dopamine receptor D2 of rat striatal membranes by [3H]-raclopride displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50081366([1-(4-Methoxy-3-phenethyloxy-benzyl)-4-methyl-pent...)
Affinity DataIC50: 200nMAssay Description:In vitro binding affinity at Sigma opioid receptor type 2 on guinea pig brain membranes by [3H]DTG displacement in the presence of [3H]pentazocine.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50081366([1-(4-Methoxy-3-phenethyloxy-benzyl)-4-methyl-pent...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro binding affinity at Dopamine receptor D2 of rat striatal membranes by [3H]-raclopride displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed