BDBM50081216 4-{5-[(R)-4-(3-Chloro-phenyl)-2-methyl-5-oxo-piperazin-1-ylmethyl]-imidazol-1-ylmethyl}-benzonitrile::CHEMBL125129

SMILES C[C@@H]1CN(C(=O)CN1Cc1cncn1Cc1ccc(cc1)C#N)c1cccc(Cl)c1

InChI Key InChIKey=HLPQICVVEMSECL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50081216   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50081216(4-{5-[(R)-4-(3-Chloro-phenyl)-2-methyl-5-oxo-piper...)
Affinity DataIC50: 80nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant human K-Ras by FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed