BDBM50081085 1-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-piperazin-1-yl)-2-phenyl-ethanone::CHEMBL87544

SMILES Nc1cccc(n1)-c1ccc(CCN2CCN(CC2)C(=O)Cc2ccccc2)cc1

InChI Key InChIKey=OGBDXFPHEQDXMH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081085   

TargetNitric oxide synthase, brain(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081085(1-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...)
Affinity DataIC50: 108nMAssay Description:Inhibitory activity against rat neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081085(1-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...)
Affinity DataIC50: 685nMAssay Description:Inhibitory activity against human endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50081085(1-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...)
Affinity DataIC50: 137nMAssay Description:Inhibitory activity against human neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed