BDBM50081070 CHEMBL3421892

SMILES Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3(CCC3)c3cc(F)ccc3Cl)C(F)(F)F)cc12

InChI Key InChIKey=PDEYZVGOCYDQJF-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50081070   

TargetProgesterone receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081070(CHEMBL3421892)
Affinity DataIC50: 0.200nMAssay Description:Binding affinity to human PRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081070(CHEMBL3421892)
Affinity DataIC50: 0.400nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081070(CHEMBL3421892)
Affinity DataIC50: 7.5nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081070(CHEMBL3421892)
Affinity DataIC50: 40nMAssay Description:Binding affinity to human ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081070(CHEMBL3421892)
Affinity DataIC50: 1.00E+3nMAssay Description:Transrepression activity at glucocorticoid receptor in human whole blood assessed as repression of IL-1-induced TNF-alpha production after 4 hrs by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081070(CHEMBL3421892)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to human ER-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50081070(CHEMBL3421892)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity to human ER-alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed