BDBM50080991 5-[1-[4-(4-Benzoyl-3-hydroxy-2-propyl-phenoxymethyl)-phenyl]-meth-(Z)-ylidene]-2-thioxo-thiazolidin-4-one::CHEMBL68595

SMILES CCCc1c(O)c(ccc1OCc1ccc(C=C2SC(S)=NC2=O)cc1)C(=O)c1ccccc1

InChI Key InChIKey=XEODKJBBFMCWBV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50080991   

TargetCathepsin D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50080991(5-[1-[4-(4-Benzoyl-3-hydroxy-2-propyl-phenoxymethy...)
Affinity DataIC50: 1.30E+3nMAssay Description:Compound was evaluated for the inhibition of cathepsin D at an enzyme level of 50 ng/mLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCathepsin D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50080991(5-[1-[4-(4-Benzoyl-3-hydroxy-2-propyl-phenoxymethy...)
Affinity DataIC50: 210nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50080991(5-[1-[4-(4-Benzoyl-3-hydroxy-2-propyl-phenoxymethy...)
Affinity DataIC50: 340nMAssay Description:Inhibitory activity against human liver Cathepsin D using Cathepsin D assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCathepsin D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50080991(5-[1-[4-(4-Benzoyl-3-hydroxy-2-propyl-phenoxymethy...)
Affinity DataIC50: 340nMAssay Description:In vitro inhibition of cathepsin D.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCathepsin D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50080991(5-[1-[4-(4-Benzoyl-3-hydroxy-2-propyl-phenoxymethy...)
Affinity DataIC50: 210nMAssay Description:Inhibition of Cathepsin D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed