BDBM50080973 3,5-Dichloro-2-(3,5-dichloro-2-hydroxy-benzenesulfonylamino)-N-[4-(6-ethoxy-benzothiazol-2-ylsulfanyl)-phenyl]-benzamide::CHEMBL83114

SMILES CCOc1ccc2nc(Sc3ccc(NC(=O)c4cc(Cl)cc(Cl)c4NS(=O)(=O)c4cc(Cl)cc(Cl)c4O)cc3)sc2c1

InChI Key InChIKey=LDOGMBNDABKFAA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50080973   

TargetCathepsin D(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50080973(3,5-Dichloro-2-(3,5-dichloro-2-hydroxy-benzenesulf...)
Affinity DataIC50: 250nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50080973(3,5-Dichloro-2-(3,5-dichloro-2-hydroxy-benzenesulf...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against human liver Cathepsin D using Cathepsin D assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetCathepsin D(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50080973(3,5-Dichloro-2-(3,5-dichloro-2-hydroxy-benzenesulf...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human liver Cathepsin D using N-succinyl-R-P-F-L-L-V-Y-7-amido-4-methylcoumarin peptide as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed