BDBM50080877 CHEMBL3421679

SMILES CC(=O)N[C@H]1Cc2ccccc2CN([C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(N)=O)C1=O

InChI Key InChIKey=MNSNXOUQPSOGHN-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50080877   

TargetMelanocyte-stimulating hormone receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50080877(CHEMBL3421679)
Affinity DataIC50: 594nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1 receptor expressed in HEK293 cells by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50080877(CHEMBL3421679)
Affinity DataEC50:  1.00E+3nMAssay Description:Activity at human MC1 receptor expressed in HEK293 cells assessed as cAMP accumulation by luminescence counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50080877(CHEMBL3421679)
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3 receptor expressed in HEK293 cells by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50080877(CHEMBL3421679)
Affinity DataEC50:  2.00E+3nMAssay Description:Activity at human MC3 receptor expressed in HEK293 cells assessed as cAMP accumulation by luminescence counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50080877(CHEMBL3421679)
Affinity DataIC50: 220nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4 receptor expressed in HEK293 cells by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50080877(CHEMBL3421679)
Affinity DataEC50:  227nMAssay Description:Agonist activity at human MC4 receptor expressed in HEK293 cells assessed as cAMP accumulation by luminescence counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50080877(CHEMBL3421679)
Affinity DataIC50: 37nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5 receptor expressed in HEK293 cells by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed