BDBM50080617 (2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(di-o-tolylmethyl-carbamoyl)-methyl]-2-[4-(2-isopropoxy-ethoxy)-phenyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL273642

SMILES CC(C)OCCOc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1C)c1ccccc1C)c1ccc2OCOc2c1)C(O)=O

InChI Key InChIKey=CMTKCIMTAINHTK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50080617   

TargetEndothelin receptor type B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50080617((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(di-o-tolylm...)
Affinity DataIC50: 1.90nMAssay Description:Binding ability determined by the displacement of [125 I]ET-3 from the human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50080617((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(di-o-tolylm...)
Affinity DataIC50: 5.17E+4nMAssay Description:Binding ability determined by the displacement of [125I]ET1 from the human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50080617((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(di-o-tolylm...)
Affinity DataIC50: 1.90nMAssay Description:Binding ability determined by the displacement of [125 I]ET-3 from the human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50080617((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(di-o-tolylm...)
Affinity DataIC50: 5.17E+4nMAssay Description:Binding ability determined by the displacement of [125I]ET1 from the human endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed