BDBM50080522 3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-carbonitrile::CHEMBL40081

SMILES FCC1Cc2ccc(cc2CN1)C#N

InChI Key InChIKey=UYOIEPOOLGXPIW-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50080522   

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50080522(3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-c...)
Affinity DataKi:  1.10E+3nMAssay Description:In vitro inhibition of PNMT (Phenylethanolamine N-Methyltransferase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50080522(3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-c...)
Affinity DataKi:  1.10E+3nMAssay Description:Affinity for bovine Phenylethanolamine N-MethyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50080522(3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-c...)
Affinity DataKi:  1.10E+3nMAssay Description:Ability to inhibit phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50080522(3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-c...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibitory constant against bovine phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50080522(3-Fluoromethyl-1,2,3,4-tetrahydro-isoquinoline-7-c...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibitory constant against human phenylethanolamine N-methyl-transferase over-expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed