BDBM50080520 3-Fluoromethyl-7-iodo-1,2,3,4-tetrahydro-isoquinoline::CHEMBL275595

SMILES FCC1Cc2ccc(I)cc2CN1

InChI Key InChIKey=VNLSZKOFVZLVCH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50080520   

TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50080520(3-Fluoromethyl-7-iodo-1,2,3,4-tetrahydro-isoquinol...)
Affinity DataKi:  70nMAssay Description:Inhibitory binding affinity for phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50080520(3-Fluoromethyl-7-iodo-1,2,3,4-tetrahydro-isoquinol...)
Affinity DataKi:  210nMAssay Description:Affinity for bovine Phenylethanolamine N-MethyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50080520(3-Fluoromethyl-7-iodo-1,2,3,4-tetrahydro-isoquinol...)
Affinity DataKi:  370nMAssay Description:Inhibitory constant against bovine phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50080520(3-Fluoromethyl-7-iodo-1,2,3,4-tetrahydro-isoquinol...)
Affinity DataKi:  660nMAssay Description:Inhibitory constant against human phenylethanolamine N-methyl-transferase over-expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed