BDBM50080449 (S)-5-Amino-2-{5-[(2-amino-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-6-ylmethyl)-amino]-1-oxo-1,3-dihydro-isoindol-2-yl}-pentanoic acid::CHEMBL117462

SMILES NCCC[C@H](N1Cc2cc(NCc3cnc4nc(N)[nH]c(=O)c4c3)ccc2C1=O)C(O)=O

InChI Key InChIKey=IRSZGKLLTGEBKA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080449   

TargetFolylpolyglutamate synthase, mitochondrial(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50080449((S)-5-Amino-2-{5-[(2-amino-4-oxo-3,4-dihydro-pyrid...)
Affinity DataKi:  1.10E+5nMAssay Description:Binding affinity as Competitive substrate in the presence of 50 gmM aminopterin towards recombinant Human Folyl-polyglutamate synthase (FPGS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed