BDBM50080255 3-[5-(Benzothiazol-2-ylmethoxy)-3-tert-butylsulfanyl-1-(4-chloro-benzyl)-1H-indol-2-yl]-2,2-dimethyl-propionic acid::CHEMBL38545

SMILES CC(C)(C)Sc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3nc4ccccc4s3)cc12

InChI Key InChIKey=YHWPKGLIJNVARR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50080255   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50080255(3-[5-(Benzothiazol-2-ylmethoxy)-3-tert-butylsulfan...)
Affinity DataIC50: 2nMAssay Description:Measuring the affinity of leukotriene synthesis inhibitor for 5-lipoxygenase activating protein by using [125I]L-691831 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50080255(3-[5-(Benzothiazol-2-ylmethoxy)-3-tert-butylsulfan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM50080255(3-[5-(Benzothiazol-2-ylmethoxy)-3-tert-butylsulfan...)
Affinity DataIC50: 360nMAssay Description:Human whole blood was stimulated with calcium ionophore (A23187) and LTB 4 measured by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article