BDBM50080146 CHEMBL3416242

SMILES Cc1cc(NS(=O)(=O)c2ccc(cc2)N2C(=O)\C(=C\c3coc4ccccc4c3=O)N=C2c2ccccc2)no1

InChI Key InChIKey=YRVLANAPTLVFNH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50080146   

TargetCarbonic anhydrase 12(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50080146(CHEMBL3416242)
Affinity DataKi:  9.70nMAssay Description:Inhibition of human membrane associated form of carbonic anhydrase-12 assessed as CO2 hydration activity incubated for 15 mins prior to testing by st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50080146(CHEMBL3416242)
Affinity DataKi:  25nMAssay Description:Inhibition of human membrane associated form of carbonic anhydrase-9 assessed as CO2 hydration activity incubated for 15 mins prior to testing by sto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50080146(CHEMBL3416242)
Affinity DataKi:  1.11E+3nMAssay Description:Inhibition of human cytosolic form of carbonic anhydrase-2 assessed as CO2 hydration activity incubated for 15 mins prior to testing by stopped flow ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50080146(CHEMBL3416242)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human cytosolic form of carbonic anhydrase-1 assessed as CO2 hydration activity incubated for 15 mins prior to testing by stopped flow ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed