BDBM50080107 CHEMBL3415998

SMILES CCN(CC)Cc1csc(n1)-c1ccc(cc1)N1C[C@H](CNC(=O)c2ccc(Cl)s2)OC1=O

InChI Key InChIKey=WBNLKANUOUTECR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50080107   

TargetCoagulation factor X(Rabbit)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50080107(CHEMBL3415998)
Affinity DataIC50: 720nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Rabbit)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50080107(CHEMBL3415998)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of F10a in rabbit plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50080107(CHEMBL3415998)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 mins by spectra max analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50080107(CHEMBL3415998)
Affinity DataIC50: 510nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of prothombin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50080107(CHEMBL3415998)
Affinity DataIC50: 820nMAssay Description:Inhibition of F10a in human plasma assessed as doubling of activated partial thromboplastin timeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2016
Entry Details Article
PubMed