BDBM50080016 (E)-1-(4-Benzyl-piperidin-1-yl)-3-(4-hydroxy-phenyl)-propenone::(E)-1-(4-benzylpiperidin-1-yl)-3-(4-hydroxy-phenyl)-propenone::1-(4-benzylpiperidin-1-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one::CHEMBL113919

SMILES Oc1ccc(\C=C\C(=O)N2CCC(Cc3ccccc3)CC2)cc1

InChI Key InChIKey=FYGULVAWGIBPEL-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50080016   

TargetAlpha-1A adrenergic receptor(Human)
University of Oregon

Curated by ChEMBL
LigandPNGBDBM50080016((E)-1-(4-Benzyl-piperidin-1-yl)-3-(4-hydroxy-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rat)
University of Oregon

Curated by ChEMBL
LigandPNGBDBM50080016((E)-1-(4-Benzyl-piperidin-1-yl)-3-(4-hydroxy-pheny...)
Affinity DataIC50: 120nMAssay Description:Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1/2B.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(Rat)
University of Oregon

Curated by ChEMBL
LigandPNGBDBM50080016((E)-1-(4-Benzyl-piperidin-1-yl)-3-(4-hydroxy-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1/2C.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Oregon

Curated by ChEMBL
LigandPNGBDBM50080016((E)-1-(4-Benzyl-piperidin-1-yl)-3-(4-hydroxy-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1/2A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50080016((E)-1-(4-Benzyl-piperidin-1-yl)-3-(4-hydroxy-pheny...)
Affinity DataIC50: 196nMAssay Description:Displacement of [3H]Ro25-6981 from NR2B NMDA receptor in rat forebrain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50080016((E)-1-(4-Benzyl-piperidin-1-yl)-3-(4-hydroxy-pheny...)
Affinity DataIC50: 131nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50080016((E)-1-(4-Benzyl-piperidin-1-yl)-3-(4-hydroxy-pheny...)
Affinity DataIC50: 196nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50080016((E)-1-(4-Benzyl-piperidin-1-yl)-3-(4-hydroxy-pheny...)
Affinity DataIC50: 104nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed