BDBM50079923 12,13-dimethoxy-5,9-dithia-3- azatricyclo[8.4.0.0 ,⁷]tetradeca-1(14),10,12- triene-2,8-dione (Compound 8)::6,7-Dimethoxy-1,10a-dihydro-2,9-dithia-3a-aza-benzo[f]azulene-4,10-dione::CHEMBL284144

SMILES COc1cc2SC(=O)C3CSCN3C(=O)c2cc1OC

InChI Key InChIKey=WEVKCUPTYBGFTJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50079923   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Nirma University

LigandPNGBDBM50079923(12,13-dimethoxy-5,9-dithia-3- azatricyclo[8.4.0.0 ...)
Affinity DataIC50: 3.31E+5nMAssay Description:HIV-1 integrase inhibitory activity of compounds were determined using strand transferase inhibitory assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2014
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50079923(12,13-dimethoxy-5,9-dithia-3- azatricyclo[8.4.0.0 ...)
Affinity DataIC50: 6.70E+5nMAssay Description:Inhibition of the 3'-processing activity of HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50079923(12,13-dimethoxy-5,9-dithia-3- azatricyclo[8.4.0.0 ...)
Affinity DataIC50: 3.33E+5nMAssay Description:Inhibition of the 3'-end joining activity of HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50079923(12,13-dimethoxy-5,9-dithia-3- azatricyclo[8.4.0.0 ...)
Affinity DataIC50: 3.31E+5nMAssay Description:Inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed