BDBM50079901 7-(methylsulfonyl)-3-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline::7-Methanesulfonyl-3-trifluoromethyl-1,2,3,4-tetrahydro-isoquinoline::CHEMBL112357

SMILES CS(=O)(=O)c1ccc2CC(NCc2c1)C(F)(F)F

InChI Key InChIKey=HKJXTMHENVDHNJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079901   

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079901BDBM50079901(7-Methanesulfonyl-3-trifluoromethyl-1,2,3,4-tetrah...)
Affinity DataKi:  3.60E+4nMAssay Description:Affinity for bovine Phenylethanolamine N-MethyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079901BDBM50079901(7-Methanesulfonyl-3-trifluoromethyl-1,2,3,4-tetrah...)
Affinity DataKi:  3.60E+4nMAssay Description:Inhibition of PNMT (Phenylethanolamine N-Methyltransferase) in vitro More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50079901BDBM50079901(7-Methanesulfonyl-3-trifluoromethyl-1,2,3,4-tetrah...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibitory activity against human PNMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed